Copy Number Variation and ecDNA effets Using HiChIP Data
- paper: https://www.biorxiv.org/content/10.1101/2024.10.03.616013v1
- code : https://github.com/emanuelepitino/Stamp_V4
- takeaway:
- no special analysists no sequencing required.
- RNA vs protein comparison was incomplete
- How the trajectory applied w/ less stringent filtering affect the performance
| STAMP | scRNA | Spatial | |
|---|---|---|---|
| Diss.cells | high | low | high |
| Cost | FixedCost | Scaled w/ cells | Fixed cost |
| Genes | Limitted to panel of known | whole transcriptome | Curated panel |